منابع مشابه
Tranexamic acid and trauma-induced coagulopathy
Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine that inhibits fibrinolysis by blocking the interaction of plasminogen with the lysine residues of fibrin. Historically, TXA is commonly used for reduction of blood loss in perioperative situations, while recently it has attracted attention for clinical use in the trauma field. In 2010, the Clinical Randomization of an Anti...
متن کاملTranexamic acid for traumatic hemorrhage.
TBE-CiTE Journal Club: January 17, 2012, with the participation of the following institutions: Trauma Research Program of the Department of Surgery of the Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada; Division of Trauma Surgery, University of Campinas, Campinas, Brazil. 1.Fellow, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada; 2. Professor...
متن کاملComparison between Topical and Oral Tranexamic Acid in Management of Traumatic Hyphema
Background: We sought to determine the efficacy of topical tranexamic acid (5%) in the management of traumatic hyphema.Methods: Thirty eyes with gross traumatic hyphema were enrolled in this study. The patients were treated with tranexamic acid (5%) eye drop every 6 hours for 5 days. The main outcome measures were best corrected visual acuity (BCVA), Intra-ocular pressure (IOP), day of clot abs...
متن کاملAcute traumatic coagulopathy.
PURPOSE OF REVIEW Recent therapeutic and observational studies have demonstrated improved survival with better management of haemostasis early after injury. This review delineates our current understanding of the clinical importance, aetiology and pathophysiology of acute traumatic coagulopathy (ATC). RECENT FINDINGS Trauma causes an acute disruption of the equilibrium between all components ...
متن کاملAcute traumatic coagulopathy.
PURPOSE OF REVIEW Mortality from trauma remains a global public health challenge, with most preventable deaths due to bleeding. The recognition of acute traumatic coagulopathy as a distinct clinical entity characterized by early coagulation dysfunction, arising prior to medical intervention, has revolutionized trauma management over the last decade. The aim of this article is to review our curr...
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ژورنال
عنوان ژورنال: Japanese Journal of Thrombosis and Hemostasis
سال: 2016
ISSN: 0915-7441,1880-8808
DOI: 10.2491/jjsth.27.436